Tauopathies Study Recruitment

Research opportunity seeks to better understand the metabolism of tau.

You, or a family member, may fit the general eligibility criteria for the research study listed below. Please note:

• This information is provided to make you aware of the study, and help direct you to where to find more information.
• This email is not a specific endorsement of whether you should or should not consider participating in the study.
• With any research study, you should carefully read the study description, contact the study coordinator for more information, and talk through any issues with your family and clinician(s) as appropriate.
• This study is enrolling persons diagnosed with PSP, CBD, or FTD due to MAPT (tau) gene mutations. Biological family members of MAPT carriers are also eligible.

Study overview
You may be eligible and interested in the opportunity to enroll in a research study that is being conducted at Washington University School of Medicine in St. Louis. This study will allow researchers to better understand the role that the protein tau has in neurodegenerative disorders.

What’s involved?
The study involves an overnight night visit and 5 follow-up lumbar puncture visits that are approximately 3 hours in length. If you agree, you will stay at the Barnes-Jewish Hospital CARS unit overnight. This unit is strictly dedicated to research and is not open to the general hospital population. For your participation, you will be compensated up to $1,210 if all study components are completed, and your travel and lodging will be paid for in advance.

Study goal
The goal of this study is to learn more about the metabolism (production and clearance) of tau in humans. Tau is a peptide that can develop tangles in neurons. Tau affects individuals with neurodegenerative disorders, and this study will help us develop future therapies for neurodegenerative disorders that have tauopathies.

Contact information
If you would consider participating or would like more information, please call Melody Li at 314-273-6062.

Study Site Details
Chihiro Sato, Ph.D.
Department of Neurology
Washington University School of Medicine
600 S. Euclid Ave., Box 8111, St. Louis, MO 63110
Melissa Sullivan, Study Coordinator (314-747-7857)

Visit the FTD Disorders Registry Find A Study webpage for information on this and other study listings.